Melanoma Program

The Yale Cancer Center Melanoma Program is a multidisciplinary team developed over 25 years ago to discover new treatments and provide state-of-the-art treatment for patients with melanoma. In order to achieve its objectives, the Melanoma Program brings together scientists, experts in clinical research, specialists in melanoma surgery, medical oncologists devoted to melanoma treatment, community oncologists, dermatologists, pathologists, dermatopathologists, and radiologists.

The foundations of this program are basic research, clinical research, and skilled multi-disciplinary care of patients. Yale Cancer Center was recently awarded the Skin SPORE grant, one of only four in the country, which supports multiple research projects in melanoma that translate basic science into clinical application. A combined clinical and laboratory program focuses on tissue microarrays, which provide a means to discover biomarkers for prognosis and response to treatment, and potential targets for drug treatment. This is closely tied to Yale's efforts to discover prognostic markers for early melanoma lesions.

The goal of the clinical research program is to introduce and investigate novel treatments for patients with melanoma. Currently, six clinical trials are available for patients with metastatic disease, including novel chemotherapy regimens, anti-angiogenesis agents (drugs that destroy or inhibit the formation of blood vessels that feed tumor), and new agents that stimulate the body's immune system to attack the melanoma tumors. In addition, patients with metastatic melanoma no longer eligible for melanoma-specific studies may be offered novel cancer treatments through the Yale Cancer Center Phase I Clinical Trial Program.

Clinical care of melanoma patients is a coordinated effort of the YCC Melanoma Program surgeons, medical oncologists, dermatologists, radiologists, surgical and dermatologic pathologists, and radiologists. Physicians meet weekly to discuss optimal multi-disciplinary management of individual patients and new research findings applicable to treatment of the disease. Clinical history, physical exam findings, surgical procedures, x-ray studies, and pathology slides are reviewed at the conference, and optimal approaches to treatment are proposed and discussed at length. The program emphasizes communication with all physicians active in the care of patients. The program and its patients benefit from the extensive experience of its members in the diagnosis, treatment, and care of patients with melanoma.

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	Ariyan, Stephan, MD	Professor of Surgery (Plastic) and of Dermatology; Clinical Program Leader, Melanoma Program, Smilow Cancer Hospital	(203) 786-3000 Appts
	Bolognia, Jean L., MD	Professor of Dermatology; Director, Pigment Lesion Clinic; Vice Chair, Clinical Affairs	(203) 789-1249 Appts (203) 776-6188 Fax
	Bosenberg, Marcus W., MD, PhD	Associate Professor of Dermatology and of Pathology	(203) 785-4094 Appts (203) 785-6869 Fax
	Cheng, David W., MD, PhD	Associate Professor of Diagnostic Radiology; Chief, Nuclear Medicine; Director, Nuclear Medicine Fellowship Program; Co-Medical Director, Yale University PET Center	(203) 200-5610 Appts
	Choi, Jennifer Nam, MD	Assistant Professor of Dermatology; Director, Yale Oncodermatology Clinic	(203) 789-1249 Appts (203) 776-6188 Fax
	Cowper, Shawn Edwin, MD	Associate Professor of Dermatology and of Pathology	(203) 785-4094 Appts (203) 785-6869 Fax
	Farber, Leonard Raymond, MD	Clinical Professor of Medicine (Medical Oncology)
	Galan, Anjela, MD	Assistant Professor of Dermatology and of Pathology	(203) 785-4094 Appts (203) 785-6869 Fax
	Glusac, Earl John, MD	Professor of Pathology and of Dermatology; Director, Physician Associate Studies	(203) 785-4094 Appts (203) 785-6869 Fax
	Imaeda, Suguru, MD	Assistant Professor of Dermatology; Director of Dermatology, Yale University Health Services; Director of Dermatology Service, Veteran Affairs Medical Center	(203) 789-1249 Appts (203) 776-6188 Fax
	Kirsch, Jonathan D, MD	Assistant Professor of Diagnostic Radiology; Deputy Chief, Ultrasound	(203) 688-2433 Appts (203) 688-9258 Fax
	Kluger, Harriet, MD	Associate Professor of Medicine (Medical Oncology); Associate Director, Hematology/Oncology Fellowship Program	(203) 200-6622 Appts (203) 737-2424 Fax
	Lazova, Rossitza, MD	Associate Professor of Dermatology and of Pathology; Director, Yale Dermatopathology Fellowship	(203) 785-4094 Appts (203) 785-6869 Fax
	Leffell, David J., MD	David P. Smith Professor of Dermatology and Professor of Surgery (Otolaryngology and Plastic); Deputy Dean for Clinical Affairs, Yale School of Medicine; Section Chief, Dermatologic Surgery and Cutaneous Oncology	(203) 785-3466 Appts (203) 785-5256 Fax
	Levy, Arthur Louis, MD	Associate Clinical Professor of Medicine (Medical Oncology)
	McNiff, Jennifer Madison, MD	Professor of Dermatology and of Pathology; Director, Yale Dermatopathology Laboratory	(203) 785-4094 Appts (203) 785-6869 Fax
	Narayan, Deepak, MD, MBBS, FRCS	Professor of Surgery (Plastic); Chief, Plastic Surgery West Haven VA	(203) 785-2571 Appts (203) 785-5714 Fax
	Rubinowitz, Ami N, MD	Associate Professor of Diagnostic Radiology; Co-Chief, Thoracic Radiology	(203) 200-5864 Appts (203) 688-3501 Fax
	Subtil, Antonio, MD, MBA	Associate Professor of Dermatology and of Pathology	(203) 785-4094 Appts (203) 785-6869 Fax
	Sznol, Mario, MD	Professor of Medicine (Medical Oncology); Vice-Chief, Medical Oncology ; Clinical Research Program Leader, Melanoma Program, Yale Cancer Center	(203) 200-6622 Appts (203) 737-2424 Fax

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